Analgesic efficacy of nimesulide in a canine osteoarthritis model
نویسندگان
چکیده
As a slowly progressive, degenerative and incapacitating disease, osteoarthritis is a common cause of morbidity in dogs. Currently available treatments are mostly symptomatic ones largely relying on anti-inflammatory / analgesic drugs. Over the past decade, veterinary medicine has seen a number of effective non-steroidal anti-inflammatory drugs (NSAIDs) introduced into practice with different modes of action, therapeutic targets, and with wide ranging efficacies, cyclooxygenase (COX)-2 selectivities, and adverse reaction profiles.
منابع مشابه
Double-blind Randomized Comparative Evaluation of Efficacy and Safety of Nimulid (nimesulide) and Diclofenac in Osteoarthritis
The efficacy and safety of Nimulid (Nimesulide) and Diclofenac was evaluated in a double blind randomized diclofenac controlled trial in patients suffering from osteoarthritis of the knee joint. Out of 141 patients, 71 (42 mates, 29female) received Nimulid 100 mg. BD and 70 patients (40 male, 30 female) received Diclofenac 75 mg BD. There was no statistically significant difference in the age, ...
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